Research Test Kit

Capturem extracellular vesicle (EV) isolation kits are a comprehensive solution for the straightforward isolation of EVs in less than 30 minutes. In order to selectively isolate EVs from a variety of biofluids, these columns employ a lectin-based binding compound. The results are muddled by the slowness, contamination removal, and damage to EVs that ultracentrifugation introduces. Other methods, such as precipitation, are inconsistent and have a low yield and purity. Our kits produce pure, intact EVs for downstream analyses, thereby facilitating the discovery of biomarkers and the advancement of diagnostic research.input:
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The Capturem Extracellular Vesicle Isolation Kit (Mini) offers a comprehensive solution for the rapid and straightforward isolation of extracellular vesicles, such as exosomes, from plasma and other small volumes of biological fluids. The kit comprises 20 single-use, disposable pre-clearing columns, 20 single-use, disposable isolation columns, and equilibrium, wash, and elution buffers. Extracellular vesicles are isolated using Capturem spin columns that are specifically designed and contain a lectin-based binding compound that is not antibody-based.Overview

Rapid, consistent isolation of highly pure, concentrated EVs from biofluid volumes of up to 850 µl (miniprep) in less than 30 minutes.The capturem method is a more efficient, gentler, and effective method than ultracentrifugation, with a sufficient yield for downstream applications.EVs that have been purified exhibit the expression of exosome protein markers and minimal to no contaminant proteins, including albumin and calnexin.A sufficient EV yield (up to 1010) is required for the downstream RT-qPCR or NGS analysis of extracellular vesicle cargo.TEM demonstrates that purified EVs exhibit classical morphology.