Leukemia Rapid Test
| Sample Type | Blood |
| Applications | For Leukemia, For Genetic Disorders |
| Analysis Mode | For Real-Time Pcr |
| Tested Parameter | For Bcr-Abl Mutations, For Bcr-Abl |
Every year, 1.9 new cases of Chronic Myelogenous Leukemia (CML) are identified per 100,000 individuals.The annual rate of increase in the prevalence of CML is estimated to be 4%, and the number of individuals living with this disease will double by 2030.Twoinput:
output:The most effective method of managing CML in most diagnosed patients is the oral administration of a Tyrosine Kinase Inhibitor (TKI) that specifically targets the activity of the BCR-ABL fusion protein. At present, a molecular diagnostic assay is necessary to evaluate the efficacy of treatment for CML by measuring the level of BCR-ABL transcript (RNA). BCR-ABL testing is conducted on patients every three months in accordance with internationally recognized standards.Three, four The quantitative results are initially normalized against a reference gene, such as ABL.Five The results are subsequently converted to an International Scale (IS) to ensure that the molecular response is reported consistently.Sixinput:
output:Only one-third of newly diagnosed CML patients are adequately monitored during the first year of treatment, despite efforts to optimize disease management.7 Consequently, in order to enhance the outcomes of CML patients, it is necessary to provide more accessible molecular testing.input:
output:The Resolutioninput:
output:Xpert BCR-ABL Ultra is a quantitative test for BCR-ABL major breakpoint (p210) transcripts that offers highly sensitive and on-demand molecular results. The entire test process, including RNA isolation, reverse transcription, and fully nested real-time PCR of the BCR-ABL target gene, is automated by Xpert BCR-ABL Ultra, which is based on the innovative GeneXpert technology.input:
output:ABL reference gene in a single, fully automated cartridge.Advantages:input:
output:Add the treated blood sample and an off-board reagent to the Xpert cartridge.
MAECENAS IACULIS
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ADIPISCING CONVALLIS BULUM
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