Dna Electrophoresis Tank

Single-cell gel electrophoresis

Reduce background DNA damage and minimize exposure to light

Enhanced resolution through high-efficiency cooling

Compatible with ethylene glycol mixtures for cooling to $°Cinput:
output:Single cell gel electrophoresis (SCGE), a technique that has gained popularity in drug toxicology and carcinogenesis studies for the detection and quantification of DNA damage in cells, is the subject of study with Cleaver Scientific Comet Assay Tanks, which are available in four slide formats. The robust construction of each tank, which is made of ebony acrylic, guarantees that cells are not exposed to background light or DNA damage during electrophoresis. Additionally, a cooled central platform provides a convenient surface for slide preparation and temperature control during the assay. DNA damage can be quantified using Comet Assay scoring software subsequent to electrophoresis.input:
output:Background: The Comet Assay (or SCGE) was initially developed in 1981 to measure double-stranded DNA breakages in single cells that were exposed to irradiation. It has since been modified to analyze specific DNA lesions and repair processes.input:
output:Summary: The size of the large genomic DNA is reduced as a result of the strand breakage of supercoiled duplex DNA, which is caused by a genotoxic insult, such as ionizing radiation. These strands are then separated or extracted by electrophoresis. The genomic DNA then assumes the appearance of a comet as its negatively charged broken ends and fragments migrate toward the anode during electrophoresis.No changes were made to the original sentence.