Automated Cell Imaging System

Optical genome mapping (OGM) with the Saphyr system is employed to routinely identify all classes of structural variants at a 5% variant allele frequency (VAF) and a resolution of 500 base pairs (bp). Saphyr is the most potent structural variant detection tool currently available, capable of identifying genomic variants that are frequently overlooked by conventional cytogenetic techniques and next-generation sequencing (NGS) technologies.input:
output:Utilize optical genome mapping to enhance your laboratory’s SV detection capabilities.

The Saphyr system enables the optical genome mapping of ultra-high molecular weight (UHMW) DNA in its native state, spanning molecules ranging from 150 kbp to multi-megabase pairs in length.input:
output:
Achieve comprehensive, impartial genomic coverage through adaptable data acquisition.

The Saphyr system’s genomic coverage is adaptable and enables the identification of heterozygous variants or rarer variants that are present in mosaic samples and heterogeneous tumors.input:
output:In as little as six hours, achieve a 100X coverage of a human genome. By simply extending the data collection time on Saphyr, it is possible to observe rarer and deeper variants without incurring any additional consumable costs. Provide SV detection down to 5% VAF and achieve 400X coverage in 24 hours. Extend the duration of the runs to achieve an even lower VAF.input:
output:Utilize the Saphyr Chip® consumable and Saphyr system to experience a seamless workflow and integration.

The Saphyr instrument is able to directly image your samples by linearizing long, labeled DNA molecules using hundreds of thousands of massively parallel nanochannels in the Saphyr Chips.input:
output:The Saphyr Chip facilitates rapid and effortless sample loading. Pipette up to three samples into individual flow cells on the chip.